| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.058ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description : | This COTL1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
| Gene Symbol: | COTL1 |
| Gene ID: | 23406 |
| Uniprot ID: | COTL1_HUMAN |
| Sample Type: | tissue homogenates or other biological fluids. |
| Tissue Specificity | Widely expressed with highest levels in placenta, lung, kidney and peripheral blood leukocytes and lower levels in brain, liver and pancreas. |
| Post Translational Modifications | |
| Function | Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis. |
| Protein Name | Coactosin-Like Protein |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | CytoplasmCytoskeletonNucleus |
| Alternative ELISA Names | Coactosin-Like Protein ELISA kitCOTL1 ELISA kitCLP ELISA kit |
| output |
Information sourced from Uniprot.org