Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.058ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This COMT Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | COMT |
Gene ID: | 1312 |
Uniprot ID: | COMT_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Brain, liver, placenta, lymphocytes and erythrocytes. |
Post Translational Modifications | The N-terminus is blocked. |
Function | Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol. |
Protein Name | Catechol O-Methyltransferase |
Database Links | Reactome: R-HSA-156581 Reactome: R-HSA-379397 Reactome: R-HSA-379398 Reactome: R-HSA-9679191 |
Cellular Localisation | Isoform Soluble: Cytoplasm Isoform Membrane-Bound: Cell Membrane Single-Pass Type Ii Membrane Protein Extracellular Side |
Alternative ELISA Names | Catechol O-Methyltransferase ELISA kit COMT ELISA kit |
output |
Information sourced from Uniprot.org