Human CNTNAP1 protein (Recombinant) (N-His) (STJP005067)

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STJP005067
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CNTNAP1-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CNTNAP1
Gene ID: 8506
Uniprot ID: CNTP1_HUMAN
Immunogen Region: Pro926-Glu1190
Immunogen: Homo sapiens (Human)
Function Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells.
Protein Name Contactin-Associated Protein 1
Caspr
Caspr1
Neurexin Iv
Neurexin-4
P190
Database Links Reactome: R-HSA-447043
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Junction
Paranodal Septate Junction
Alternative Protein Names Contactin-Associated Protein 1 protein
Caspr protein
Caspr1 protein
Neurexin Iv protein
Neurexin-4 protein
P190 protein
CNTNAP1 protein
CASPR protein
NRXN4 protein

Information sourced from Uniprot.org

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