| Host: | E.coli |
| Applications: | SDS-PAGE/Bioactivity |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Human CNTF-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.5) containing 1mM DTT, 30% Glycerol, 0.2M NaCl |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin: | < 1 EU per 1ug of protein (determined by LAL method) |
| Immunoreactivity: | Measured in a cell proliferation assay using TF-1 human erythroleukemic cell. The ED50 range ≤ 1ug/ml. |
| Gene Symbol: | CNTF |
| Gene ID: | 1270 |
| Uniprot ID: | CNTF_HUMAN |
| Immunogen Region: | 1-200aa |
| Accession Number: | NP_000605 |
| Immunogen: | Human |
| Immunogen Sequence: |
| Tissue Specificity | Nervous system. |
| Function | CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. |
| Protein Name | Ciliary Neurotrophic FactorCntf |
| Database Links | Reactome: R-HSA-6788467 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Ciliary Neurotrophic Factor proteinCntf proteinCNTF protein |
Information sourced from Uniprot.org