Human CNMD protein (Recombinant) (N-His) (STJP003382)

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STJP003382
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CNMD-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CNMD
Gene ID: 11061
Uniprot ID: CNMD_HUMAN
Immunogen Region: Lys134-Val334
Immunogen: Homo sapiens (Human)
Post Translational Modifications After cleavage, the post-translationally modified ChM-I is secreted as a glycoprotein.
Function Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
Protein Name Leukocyte Cell-Derived Chemotaxin 1
Chondromodulin Cleaved Into - Chondrosurfactant Protein
Ch-Sp - Chondromodulin-1
Chondromodulin-I
Chm-I
Cellular Localisation Chondromodulin-1: Secreted
Extracellular Space
Extracellular Matrix
Accumulated In The Inter-Territorial Matrix Of Cartilage
Chondrosurfactant Protein: Endomembrane System
Single-Pass Membrane Protein
Alternative Protein Names Leukocyte Cell-Derived Chemotaxin 1 protein
Chondromodulin Cleaved Into - Chondrosurfactant Protein protein
Ch-Sp - Chondromodulin-1 protein
Chondromodulin-I protein
Chm-I protein
CNMD protein
CHMI protein
LECT1 protein
MYETS1 protein

Information sourced from Uniprot.org

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