• Biotinylated Human CLEC12A on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human CLEC12A is greater than 95% as determined by SEC-HPLC.
  • Immobilized Anti-CLEC12A Antibody, hFc Tag at 1 Mu g/ml (100 Mu l/well) on the plate. Dose response curve for Biotinylated Human CLEC12A, His Tag with the EC50 of 0. 41 Mu g/ml determined by ELISA.

Human CLEC12A/MICL/CLL-1 protein (Recombinant) (N-His, C-Avi) {Biotin} (STJP001721)

SKU:
STJP001721

$834.98 - $2,577.83
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human CLEC12A/MICL/CLL-1-N-His, C-Avi protein was developed from hek293 and has a target region of N-His, C-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: CLEC12A
Gene ID: 160364
Uniprot ID: CL12A_HUMAN
Immunogen Region: His65-Ala265
Immunogen: DNA sequence encoding Human CLEC12A/MICL/CLL-1 including a N-His, C-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Post Translational Modifications Highly N-glycosylated. Glycosylation varies between cell types.
Function Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.
Protein Name C-Type Lectin Domain Family 12 Member A
C-Type Lectin-Like Molecule 1
Cll-1
Dendritic Cell-Associated Lectin 2
Dcal-2
Myeloid Inhibitory C-Type Lectin-Like Receptor
Micl
Cd Antigen Cd371
Database Links Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Ligand Binding Leads To Internalization
Alternative Protein Names C-Type Lectin Domain Family 12 Member A protein
C-Type Lectin-Like Molecule 1 protein
Cll-1 protein
Dendritic Cell-Associated Lectin 2 protein
Dcal-2 protein
Myeloid Inhibitory C-Type Lectin-Like Receptor protein
Micl protein
Cd Antigen Cd371 protein
CLEC12A protein
CLL1 protein
DCAL2 protein
MICL protein

Information sourced from Uniprot.org

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