Human CLCA4 protein (Recombinant) (N-His) (STJP015926)

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STJP015926
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Host: E.coli
Applications: ELISA/Immunogen/SDS-PAGE/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CLCA4-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: Please contact us for further information.
Gene Symbol: CLCA4
Gene ID: 22802
Uniprot ID: CLCA4_HUMAN
Immunogen Region: Ser22-Lys301
Immunogen: Homo sapiens (Human)
Post Translational Modifications The translation product is autoproteolytically cleaved by the metalloprotease domain in the endoplasmic reticulum into a N-terminal and a C-terminal products that remain physically associated with each other. The cleavage is necessary for calcium-activated chloride channel (CaCC) activation activity.
Function May be involved in mediating calcium-activated chloride conductance.
Protein Name Calcium-Activated Chloride Channel Regulator 4
Calcium-Activated Chloride Channel Family Member 4
Hclca4
Calcium-Activated Chloride Channel Protein 2
Cacc-2
Hcacc-2
Chloride Channel Accessory 4 Cleaved Into - Calcium-Activated Chloride Channel Regulator 4 - 110 Kda Form - Calcium-Activated Chloride Channel Regulator 4 - 30 Kda Form
Database Links Reactome: R-HSA-2672351
Cellular Localisation Cell Membrane
Single-Pass Membrane Protein
Apical Cell Membrane
Secreted
The C-Terminus 30 Kda Form Is Anchored To The Membrane
The N-Terminus 110 Kda Form Is Released From The Membrane Triggered By An Unknown Stimulus
Alternative Protein Names Calcium-Activated Chloride Channel Regulator 4 protein
Calcium-Activated Chloride Channel Family Member 4 protein
Hclca4 protein
Calcium-Activated Chloride Channel Protein 2 protein
Cacc-2 protein
Hcacc-2 protein
Chloride Channel Accessory 4 Cleaved Into - Calcium-Activated Chloride Channel Regulator 4 - 110 Kda Form - Calcium-Activated Chloride Channel Regulator 4 - 30 Kda Form protein
CLCA4 protein
CaCC2 protein
UNQ562 protein
PRO1124 protein

Information sourced from Uniprot.org

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