| Short Description : | Recombinant-Active-Human CHIT1-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its ability to cleave 4-Methylumbelliferylbeta-D-N, N NA, N”-triacetylchitotriose (4-MU-TACT). The specific activity is >1, 500 pmol/min/µg, as measured under the described conditions. |
| Gene Symbol: | CHIT1 |
| Gene ID: | 1118 |
| Uniprot ID: | CHIT1_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Ala22-Asn466 |
| Function | Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity. |
| Protein Name | Chitotriosidase-1Chitinase-1 |
| Database Links | Reactome: R-HSA-189085Reactome: R-HSA-6798695 |
| Cellular Localisation | SecretedLysosomeA Small Proportion Is Lysosomal |
| Alternative Protein Names | Chitotriosidase-1 proteinChitinase-1 proteinCHIT1 protein |
Information sourced from Uniprot.org
