Name: Human CFLAR (CASP8 And FADD Like Apoptosis Regulator) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014279)
SKU: STJE0014279
Availability: InStock

General Information
Product Properties
Target Information
Additional Info
Product Review

Applications:	ELISA
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	0.061ng/mL
Detection Limit:	0.156-10ng/mL
Short Description :	This CFLAR Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids..

Storage Instruction:	The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	3 hrs

Gene Symbol:	CFLAR
Gene ID:	8837
Uniprot ID:	CFLAR_HUMAN
Immunogen Region:	Ready-To-Use
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity	Widely expressed. Higher expression in skeletal muscle, pancreas, heart, kidney, placenta, and peripheral blood leukocytes. Also detected in diverse cell lines. Isoform 8 is predominantly expressed in testis and skeletal muscle.
Post Translational Modifications	Proteolytically processed by CASP8 generating subunit p43 and p12.
Function	Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
Protein Name	Casp8 And Fadd-Like Apoptosis Regulator Caspase Homolog Cash Caspase-Eight-Related Protein Casper Caspase-Like Apoptosis Regulatory Protein Clarp Cellular Flice-Like Inhibitory Protein C-Flip Fadd-Like Antiapoptotic Molecule 1 Flame-1 Inhibitor Of Flice I-Flice Mach-Related Inducer Of Toxicity Mrit Usurpin Cleaved Into - Casp8 And Fadd-Like Apoptosis Regulator Subunit P43 - Casp8 And Fadd-Like Apoptosis Regulator Subunit P12
Database Links	Reactome: R-HSA-3371378 O15519-1 Reactome: R-HSA-5213460 Reactome: R-HSA-5218900 Reactome: R-HSA-5357905 O15519-1 Reactome: R-HSA-69416 O15519-2 Reactome: R-HSA-75158
Cellular Localisation
Alternative ELISA Names	Casp8 And Fadd-Like Apoptosis Regulator ELISA kit Caspase Homolog ELISA kit Cash ELISA kit Caspase-Eight-Related Protein ELISA kit Casper ELISA kit Caspase-Like Apoptosis Regulatory Protein ELISA kit Clarp ELISA kit Cellular Flice-Like Inhibitory Protein ELISA kit C-Flip ELISA kit Fadd-Like Antiapoptotic Molecule 1 ELISA kit Flame-1 ELISA kit Inhibitor Of Flice ELISA kit I-Flice ELISA kit Mach-Related Inducer Of Toxicity ELISA kit Mrit ELISA kit Usurpin Cleaved Into - Casp8 And Fadd-Like Apoptosis Regulator Subunit P43 - Casp8 And Fadd-Like Apoptosis Regulator Subunit P12 ELISA kit CFLAR ELISA kit CASH ELISA kit CASP8AP1 ELISA kit CLARP ELISA kit MRIT ELISA kit
output

Information sourced from Uniprot.org

Model	Name	Reactivity	Application
STJE0007904	Human CFLAR (CASP8 And FADD Like Apoptosis Regulator) Sandwich ELISA Kit Kit (STJE0007904)	Human	ELISA
STJE0013711	Human ASK1 (Apoptosis Signal Regulating Kinase 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013711)	Human	ELISA
STJE0000397	Human CASP8 (CASP8) Sandwich ELISA Kit Kit (STJE0000397)	Human	ELISA
STJE0002317	Human BAX (Apoptosis regulator BAX) Sandwich ELISA Kit (STJE0002317)	Human	ELISA
STJE0015699	Human GROg (Growth Regulated Oncogene Gamma) Sandwich ELISA Kit Ready-To-Use Kit (STJE0015699)	Human	ELISA

Human CFLAR (CASP8 And FADD Like Apoptosis Regulator) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014279)

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