Human CFD protein (Recombinant) (C-His) (STJP008658)

Name: Human CFD protein (Recombinant) (C-His) (STJP008658)
SKU: STJP008658
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ImmunogenHomo sapiens (Human)

STJP008658

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Short Description	Recombinant-Human CFD-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Serine protease that initiates the alternative pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. In contrast to other complement pathways (classical, lectin and GZMK) that are directly activated by pathogens or antigen-antibody complexes, the alternative complement pathway is initiated by the spontaneous hydrolysis of complement C3. The alternative complement pathway acts as an amplification loop that enhances complement activation by mediating the formation of C3 and C5 convertases. Activated CFD cleaves factor B (CFB) when the latter is complexed with complement C3b, activating the C3 convertase of the alternative pathway.
Protein Name	Complement Factor D Adipsin C3 Convertase Activator Properdin Factor D
Database Links	Reactome: R-HSA-114608 Reactome: R-HSA-173736 Reactome: R-HSA-6798695
Cellular Localisation	Secreted
Alternative Protein Names	Complement Factor D protein Adipsin protein C3 Convertase Activator protein Properdin Factor D protein CFD protein DF protein PFD protein

Information sourced from Uniprot.org