Human CES2 protein (Recombinant) (N-GST) (STJP003172)

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STJP003172
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Short Description :Recombinant-Human CES2-N-GST protein was developed from e.coli for the region N-GST. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:CES2
Gene ID:8824
Uniprot ID:EST2_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:His452-Leu559
Post Translational Modifications Glycosylated.
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine. Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins.
Protein Name Cocaine Esterase
Carboxylesterase 2
Ce-2
Hce-2
Methylumbelliferyl-Acetate Deacetylase 2
Database Links Reactome: R-HSA-211945
Reactome: R-HSA-9749641
Cellular Localisation Endoplasmic Reticulum Lumen
Alternative Protein Names Cocaine Esterase protein
Carboxylesterase 2 protein
Ce-2 protein
Hce-2 protein
Methylumbelliferyl-Acetate Deacetylase 2 protein
CES2 protein
ICE protein

Information sourced from Uniprot.org