Human CES2 protein (Recombinant-Active) (C-10*His) (STJP011716)

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STJP011716-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human CES2-C-10*His protein was developed from mammalian cells and has a target region of C-10*His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: CES2
Gene ID: 8824
Uniprot ID: EST2_HUMAN
Immunogen Region: Gln27-Leu559
Immunogen: Homo sapiens (Human)
Post Translational Modifications Glycosylated.
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of cocaine, 4-methylumbelliferyl acetate, heroin and 6-monoacetylmorphine. Hydrolyzes aspirin, substrates with large alcohol group and small acyl group and endogenous lipids such as triacylglycerol. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins.
Protein Name Cocaine Esterase
Carboxylesterase 2
Ce-2
Hce-2
Methylumbelliferyl-Acetate Deacetylase 2
Database Links Reactome: R-HSA-211945
Reactome: R-HSA-9749641
Cellular Localisation Endoplasmic Reticulum Lumen
Alternative Protein Names Cocaine Esterase protein
Carboxylesterase 2 protein
Ce-2 protein
Hce-2 protein
Methylumbelliferyl-Acetate Deacetylase 2 protein
CES2 protein
ICE protein

Information sourced from Uniprot.org

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