SDS-PAGE gel of recombinant human CERT1 protein 3ug reducing conditions Coomassie blue stain

Human CERT1 protein (Recombinant) (His-Tag) (STJP016719)

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STJP016719
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Short Description :Recombinant-Human CERT1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:0.5 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol 0.1M NaCl
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:CERT1
Gene ID:10087
Uniprot ID:CERT_HUMAN
Accession Number:NP_112729
Immunogen:Human
Immunogen Region:347-598aa
Immunogen Sequence:LH WPTSLPSGDA FSSVGTHRFV QKVEEMVQNH MTYSLQDVGG DANWQLVVEE GEMKVYRREV EENGIVLDPL KATHAVKGVT GHEVCNYFWN VDVRNDWETT IENFHVVETL ADNAIIIYQT HKRVWPASQR DVLYLSVIRK IPALTENDPE TWIVCNFSVD HDSAPLNNRC VRAKINVAMI CQTLVS
Tissue Specificity Widely expressed.
Post Translational Modifications Phosphorylation on Ser-132 decreases the affinity toward phosphatidylinositol 4-phosphate at Golgi membranes and reduces ceramide transfer activity. Inactivated by hyperphosphorylation of serine residues by CSNK1G2/CK1 that triggers dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis.
Function Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner.
Protein Name Ceramide Transfer Protein
Hcert
Collagen Type Iv Alpha-3-Binding Protein
Goodpasture Antigen-Binding Protein
Gpbp
Start Domain-Containing Protein 11
Stard11
Star-Related Lipid Transfer Protein 11
Database Links Reactome: R-HSA-1660661 Q9Y5P4-2
Cellular Localisation Cytoplasm
Golgi Apparatus
Endoplasmic Reticulum
Preferentially Localized To The Golgi Apparatus
Alternative Protein Names Ceramide Transfer Protein protein
Hcert protein
Collagen Type Iv Alpha-3-Binding Protein protein
Goodpasture Antigen-Binding Protein protein
Gpbp protein
Start Domain-Containing Protein 11 protein
Stard11 protein
Star-Related Lipid Transfer Protein 11 protein
CERT1 protein
CERT protein
COL4A3BP protein
STARD11 protein

Information sourced from Uniprot.org

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