| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | <0.001 EU/Mu g |
| Gene Symbol: | CDNF |
| Gene ID: | 441549 |
| Uniprot ID: | CDNF_HUMAN |
| Immunogen: | Recombinant Human Cerebral dopamine neurotrophic factor/CDNF Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln27-Leu187) of human Cerebral dopamine neurotrophic factor/CDNF (Accession #NP_001025 |
| Immunogen Region: | Gln27-Leu187 |
| Immunogen Sequence: | QEAGGRPGADCEVCKEFLNR FYKSLIDRGVNFSLDTIEKE LISFCLDTKGKENRLCYYLG ATKDAATKILSEVTRPMSVH MPAMKICEKLKKLDSQICEL KYEKTLDLASVDLRKMRVAE LKQILHSWGEECRACAEKTD YVNLIQELAPKYAATHPKTE L |
| Function | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. |
| Protein Name | Cerebral Dopamine Neurotrophic FactorArmet-Like Protein 1Conserved Dopamine Neurotrophic Factor |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Cerebral Dopamine Neurotrophic Factor proteinArmet-Like Protein 1 proteinConserved Dopamine Neurotrophic Factor proteinCDNF proteinARMETL1 protein |
Information sourced from Uniprot.org
