| Host: | HEK293 cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Formulation: | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method: | < 0.1 EU/Mu g of the protein by LAL method. |
| Gene Symbol: | GPA33 |
| Gene ID: | 10223 |
| Uniprot ID: | GPA33_HUMAN |
| Immunogen: | Recombinant Human Cell surface A33 antigen/GPA33 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ile22-Val235) of human GPA33/Glycoprotein-A33 (Accession #NP_005805.1) fused with a 6×His tag at th |
| Immunogen Sequence: | ISVETPQDVLRASQGKSVTL PCTYHTSTSSREGLIQWDKL LLTHTERVVIWPFSNKNYIH GELYKNRVSISNNAEQSDAS ITIDQLTMADNGTYECSVSL MSDLEGNTKSRVRLLVLVPP SKPECGIEGETIIGNNIQLT CQSKEGSPTPQYSWKRYNIL NQEQPLAQPASGQPVSLKNI STDTSGYYICTSSNEEGTQF CNITVAVRSPSMNV |
| Tissue Specificity | Expressed in normal gastrointestinal epithelium and in 95% of colon cancers. |
| Post Translational Modifications | N-glycosylated, contains approximately 8 kDa of N-linked carbohydrate. Palmitoylated. |
| Function | May play a role in cell-cell recognition and signaling. |
| Protein Name | Cell Surface A33 AntigenGlycoprotein A33 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cell Surface A33 Antigen proteinGlycoprotein A33 proteinGPA33 protein |
Information sourced from Uniprot.org