Human CEACAM8/CD66b protein (Recombinant) (C-His&Avi) {Biotin} (STJP019961)

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STJP019961-100
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Covered by St John's Laboratory Guarantee

Host: HEK293 cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation: Biotin
Formulation: Lyophilised from 0.22 Mu m filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Determination Method: < 1 EU/Mu g of the protein by LAL method.
Gene Symbol: CEACAM8
Gene ID: 1088
Uniprot ID: CEAM8_HUMAN
Immunogen Region: Gln35-Ser319
Immunogen: Biotinylated Recombinant Human CEACAM8/CD66b Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gln35-Ser319) of Human CEACAM8/CD66b (Accession #P31997) fused with a C-His&Avi tag at the C-terminus.
Immunogen Sequence: QLTIEAVPSNAAEGKEVLLL VHNLPQDPRGYNWYKGETVD ANRRIIGYVISNQQITPGPA YSNRETIYPNASLLMRNVTR NDTGSYTLQVIKLNLMSEEV TGQFSVHPETPKPSISSNNS NPVEDKDAVAFTCEPETQNT TYLWWVNGQSLPVSPRLQLS NGNRTLTLLSVTRNDVGPYE CEIQNPASANFSDPVTLNVL YGPDAPTISPSDTYYHAGVN LNLSCHAASNPPSQYSWSV
Tissue Specificity Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
Post Translational Modifications Glycosylated.
Function Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.
Protein Name Cell Adhesion Molecule Ceacam8
Cd67 Antigen
Carcinoembryonic Antigen Cgm6
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8
Cea Cell Adhesion Molecule 8
Non-Specific Cross-Reacting Antigen Nca-95
Cd Antigen Cd66b
Database Links Reactome: R-HSA-1566977
Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Cell Surface
Alternative Protein Names Cell Adhesion Molecule Ceacam8 protein
Cd67 Antigen protein
Carcinoembryonic Antigen Cgm6 protein
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8 protein
Cea Cell Adhesion Molecule 8 protein
Non-Specific Cross-Reacting Antigen Nca-95 protein
Cd Antigen Cd66b protein
CEACAM8 protein
CGM6 protein

Information sourced from Uniprot.org

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