• Biotinylated Human CEACAM-6 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human CEACAM-6 is greater than 95% as determined by SEC-HPLC.
  • Human CEACAM-8, His Tag immobilized on CM5 Chip can bind Biotinylated Human CEACAM6, His-Avi Tag with an affinity constant of 3. 81 Mu M as determined in SPR assay (Biacore T200).

Human CEACAM-6/CD66c protein (Recombinant) (C-His-Avi) {Biotin} (STJP001657)

SKU:
STJP001657

£597.50 - £1,839.50
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human CEACAM-6/CD66c-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: CEACAM6
Gene ID: 4680
Uniprot ID: CEAM6_HUMAN
Immunogen Region: Lys35-Gly320
Immunogen: DNA sequence encoding Human CEACAM-6/CD66c including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Post Translational Modifications Glycosylated.
Function Cell surface glycoprotein that plays a role in cell adhesion and tumor progression. Intercellular adhesion occurs in a calcium- and fibronectin-independent manner. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM5 and CEACAM8. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. Plays a role in neutrophil adhesion to cytokine-activated endothelial cells. Plays a role in cell migration and cell adhesion to endothelial cells.
Protein Name Cell Adhesion Molecule Ceacam6
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6
Cea Cell Adhesion Molecule 6
Non-Specific Crossreacting Antigen
Normal Cross-Reacting Antigen
Cd Antigen Cd66c
Database Links Reactome: R-HSA-1566977
Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Apical Cell Membrane
Cell Surface
Localized To The Apical Glycocalyx Surface
Alternative Protein Names Cell Adhesion Molecule Ceacam6 protein
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 protein
Cea Cell Adhesion Molecule 6 protein
Non-Specific Crossreacting Antigen protein
Normal Cross-Reacting Antigen protein
Cd Antigen Cd66c protein
CEACAM6 protein
NCA protein

Information sourced from Uniprot.org

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