Human CDw293/BMPR1B protein (Recombinant) (C-Fc) (STJP006989)

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STJP006989
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CDw293/BMPR1B-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: BMPR1B
Gene ID: 658
Uniprot ID: BMR1B_HUMAN
Immunogen Region: Lys14-Arg126
Immunogen: Homo sapiens (Human)
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.
Protein Name Bone Morphogenetic Protein Receptor Type-1b
Bmp Type-1b Receptor
Bmpr-1b
Cd Antigen Cdw293
Database Links Reactome: R-HSA-201451
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Bone Morphogenetic Protein Receptor Type-1b protein
Bmp Type-1b Receptor protein
Bmpr-1b protein
Cd Antigen Cdw293 protein
BMPR1B protein

Information sourced from Uniprot.org

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