| Short Description : | Recombinant-Human CDNF-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | < 1 EU/µg as determined by LAL test. |
| Gene Symbol: | CDNF |
| Gene ID: | 441549 |
| Uniprot ID: | CDNF_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Gln25-Leu187 |
| Function | Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra. |
| Protein Name | Cerebral Dopamine Neurotrophic FactorArmet-Like Protein 1Conserved Dopamine Neurotrophic Factor |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Cerebral Dopamine Neurotrophic Factor proteinArmet-Like Protein 1 proteinConserved Dopamine Neurotrophic Factor proteinCDNF proteinARMETL1 protein |
Information sourced from Uniprot.org
