• Biotinylated Human CD93 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
  • The purity of Biotinylated Human CD93 is greater than 95% as determined by SEC-HPLC.
  • Biotinylated Human CD93, His-Avi Tag immobilized on CM5 Chip can bind Human IGFBP-7, His Tag with an affinity constant of 0. 17 Mu M as determined in SPR assay (Biacore T200).

Human CD93/C1q R1 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001565)

SKU:
STJP001565

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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human CD93/C1q R1-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: CD93
Gene ID: 22918
Uniprot ID: C1QR1_HUMAN
Immunogen Region: Thr22-Lys580
Immunogen: DNA sequence encoding Human CD93/C1q R1 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Post Translational Modifications N- and O-glycosylated.
Function Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.
Protein Name Complement Component C1q Receptor
C1q/Mbl/Spa Receptor
C1qr
C1qr(P
C1qrp
Cdw93
Complement Component 1 Q Subcomponent Receptor 1
Matrix-Remodeling-Associated Protein 4
Cd Antigen Cd93
Database Links Reactome: R-HSA-6798695
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Complement Component C1q Receptor protein
C1q/Mbl/Spa Receptor protein
C1qr protein
C1qr(P protein
C1qrp protein
Cdw93 protein
Complement Component 1 Q Subcomponent Receptor 1 protein
Matrix-Remodeling-Associated Protein 4 protein
Cd Antigen Cd93 protein
CD93 protein
C1QR1 protein
MXRA4 protein

Information sourced from Uniprot.org

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