Host: |
HEK293 |
Note: |
STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Recombinant-Human CD93/C1q R1-C-His-Avi protein was developed from hek293 and has a target region of C-His-Avi. For use in research applications. |
Conjugation: |
Biotin |
Formulation: |
Lyophilised from 0.2 µm filtered PBS solution pH7.4. |
Dilution Range: |
Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM |
Storage Instruction: |
The lyophilized protein is stable for at least 1 year from date of receipt at-20°C. |
Endotoxin: |
Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). |
Gene Symbol: |
CD93 |
Gene ID: |
22918 |
Uniprot ID: |
C1QR1_HUMAN |
Immunogen Region: |
Thr22-Lys580 |
Immunogen: |
DNA sequence encoding Human CD93/C1q R1 including a C-His-Avi tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology. |
Post Translational Modifications | N- and O-glycosylated. |
Function | Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion. |
Protein Name | Complement Component C1q ReceptorC1q/Mbl/Spa ReceptorC1qrC1qr(PC1qrpCdw93Complement Component 1 Q Subcomponent Receptor 1Matrix-Remodeling-Associated Protein 4Cd Antigen Cd93 |
Database Links | Reactome: R-HSA-6798695 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Protein Names | Complement Component C1q Receptor proteinC1q/Mbl/Spa Receptor proteinC1qr proteinC1qr(P proteinC1qrp proteinCdw93 proteinComplement Component 1 Q Subcomponent Receptor 1 proteinMatrix-Remodeling-Associated Protein 4 proteinCd Antigen Cd93 proteinCD93 proteinC1QR1 proteinMXRA4 protein |
Information sourced from Uniprot.org
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