Name: Human CD85a/LILRB3 protein (Recombinant) (C-His) (STJP006999)
SKU: STJP006999
Availability: InStock

Human CD85a/LILRB3 protein (Recombinant) (C-His) (STJP006999)

SKU:

STJP006999

£469.50 - £2,492.50

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Host:	Mammalian Cells
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human CD85a/LILRB3-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	Phosphorylated on tyrosine residues by LYN. Phosphorylation at Tyr-595 and Tyr-625 is important for interaction with PTPN6/SHP-1 and PTPN11/SHP-2.
Function	May act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. Down-regulates antigen-induced B-cell activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM).
Protein Name	Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 Lir-3 Leukocyte Immunoglobulin-Like Receptor 3 Cd85 Antigen-Like Family Member A Immunoglobulin-Like Transcript 5 Ilt-5 Monocyte Inhibitory Receptor Hl9 Cd Antigen Cd85a
Database Links	Reactome: R-HSA-198933 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 3 protein Lir-3 protein Leukocyte Immunoglobulin-Like Receptor 3 protein Cd85 Antigen-Like Family Member A protein Immunoglobulin-Like Transcript 5 protein Ilt-5 protein Monocyte Inhibitory Receptor Hl9 protein Cd Antigen Cd85a protein LILRB3 protein ILT5 protein LIR3 protein

Information sourced from Uniprot.org

Model	Name	Host	Clonality	Reactivity	Application
STJP003332	Human CD85a/LILRB3 protein (Recombinant) (N-His) (STJP003332)	E. coli
STJP001428	Human LILRB3/ILT-5/CD85a protein (Recombinant) (C-His&Avi) (STJP001428)	HEK293 cells
STJP001649	Human LILRB3/CD85a/ILT5 protein (Recombinant) (C-His-Avi) {Biotin} (STJP001649)	HEK293
STJP012196	Mouse Pirb/Lilrb3 protein (Recombinant-Active) (C-His) (STJP012196)	Mammalian Cells
STJA0027757	Anti-CD85a/LILRB3 antibody [A1] (STJA0027757)	Human	Monoclonal	Human	ELISA/FC

Human CD85a/LILRB3 protein (Recombinant) (C-His) (STJP006999)

General Information