Human CD66d/CEACAM3 protein (Recombinant) (N-His) (STJP004674)

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STJP004674
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD66d/CEACAM3-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CEACAM3
Gene ID: 1084
Uniprot ID: CEAM3_HUMAN
Immunogen Region: Lys35-Gly155
Immunogen: Homo sapiens (Human)
Post Translational Modifications Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected.
Function Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
Protein Name Cell Adhesion Molecule Ceacam3
Carcinoembryonic Antigen Cgm1
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3
Cea Cell Adhesion Molecule 3
Cd Antigen Cd66d
Database Links Reactome: R-HSA-202733
Reactome: R-HSA-6798695
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Cell Adhesion Molecule Ceacam3 protein
Carcinoembryonic Antigen Cgm1 protein
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 protein
Cea Cell Adhesion Molecule 3 protein
Cd Antigen Cd66d protein
CEACAM3 protein
CD66D protein
CGM1 protein

Information sourced from Uniprot.org

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