| Short Description : | Recombinant-Active-Human CD66b/CEACAM8-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. When recombinant human Galectin‑3 is coated at 2 Mu g/mL, 100 Mu L/well, it binds to recombinant CD66b/CEACAM8 with an ED50 of 0.4-2.4 Mu g/mL. |
| Gene Symbol: | CEACAM8 |
| Gene ID: | 1088 |
| Uniprot ID: | CEAM8_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Gln35-Asp320 |
| Post Translational Modifications | Glycosylated. |
| Function | Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils. |
| Protein Name | Cell Adhesion Molecule Ceacam8Cd67 AntigenCarcinoembryonic Antigen Cgm6Carcinoembryonic Antigen-Related Cell Adhesion Molecule 8Cea Cell Adhesion Molecule 8Non-Specific Cross-Reacting Antigen Nca-95Cd Antigen Cd66b |
| Database Links | Reactome: R-HSA-1566977Reactome: R-HSA-202733Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorCell Surface |
| Alternative Protein Names | Cell Adhesion Molecule Ceacam8 proteinCd67 Antigen proteinCarcinoembryonic Antigen Cgm6 proteinCarcinoembryonic Antigen-Related Cell Adhesion Molecule 8 proteinCea Cell Adhesion Molecule 8 proteinNon-Specific Cross-Reacting Antigen Nca-95 proteinCd Antigen Cd66b proteinCEACAM8 proteinCGM6 protein |
Information sourced from Uniprot.org