Human CD38/ADPRC 1 protein (Recombinant-Active) (C-His) (STJP011955)

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STJP011955-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human CD38/ADPRC 1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: CD38
Gene ID: 952
Uniprot ID: CD38_HUMAN
Immunogen Region: Val43-Ile300
Immunogen: Homo sapiens (Human)
Function Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion. Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP(+), while preferentially cleaving NADP(+) to cADPR and ADPRP rather than into NADDP(+). Has cADPR hydrolase activity.
Protein Name Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1
2'-Phospho-Adp-Ribosyl Cyclase
2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase
2'-Phospho-Cyclic-Adp-Ribose Transferase
Adp-Ribosyl Cyclase 1
Adprc 1
Cyclic Adp-Ribose Hydrolase 1
Cadpr Hydrolase 1
T10
Cd Antigen Cd38
Database Links Reactome: R-HSA-196807
Cellular Localisation Cell Surface
Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Adp-Ribosyl Cyclase/Cyclic Adp-Ribose Hydrolase 1 protein
2'-Phospho-Adp-Ribosyl Cyclase protein
2'-Phospho-Adp-Ribosyl Cyclase/2'-Phospho-Cyclic-Adp-Ribose Transferase protein
2'-Phospho-Cyclic-Adp-Ribose Transferase protein
Adp-Ribosyl Cyclase 1 protein
Adprc 1 protein
Cyclic Adp-Ribose Hydrolase 1 protein
Cadpr Hydrolase 1 protein
T10 protein
Cd Antigen Cd38 protein
CD38 protein

Information sourced from Uniprot.org

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