| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Recombinant-Active-Human CD370/CLEC9A-N-hFc protein was developed from mammalian cells and has a target region of N-hFc. For use in research applications. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Gene Symbol: | CLEC9A |
| Gene ID: | 283420 |
| Uniprot ID: | CLC9A_HUMAN |
| Immunogen Region: | Lys57-Val241 |
| Immunogen: | Homo sapiens (Human) |
| Post Translational Modifications | N-glycosylated. |
| Function | Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner. |
| Protein Name | C-Type Lectin Domain Family 9 Member ACd Antigen Cd370 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | C-Type Lectin Domain Family 9 Member A proteinCd Antigen Cd370 proteinCLEC9A proteinUNQ9341 proteinPRO34046 protein |
Information sourced from Uniprot.org