Human CD357/TNFRSF18/GITR protein (Recombinant) (C-Fc) (STJP013618)

SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
STJP013618-100
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General Information

Short DescriptionRecombinant-Human CD357/TNFRSF18/GITR-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications.
ApplicationsELISA/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin< 1 EU/µg as determined by LAL test.

Target Information

Gene SymbolTNFRSF18
Gene ID8784
Uniprot IDTNR18_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionGln26-Gln161

Additional Info

Function Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 18
Activation-Inducible Tnfr Family Receptor
Glucocorticoid-Induced Tnfr-Related Protein
Cd Antigen Cd357
Database Links Reactome: R-HSA-5669034
Reactome: R-HSA-8877330
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Secreted
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 18 protein
Activation-Inducible Tnfr Family Receptor protein
Glucocorticoid-Induced Tnfr-Related Protein protein
Cd Antigen Cd357 protein
TNFRSF18 protein
AITR protein
GITR protein
UNQ319 protein
PRO364 protein

Information sourced from Uniprot.org

Citations

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