Human CD339/JAG1 protein (Recombinant) (C-Fc) (STJP013395)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD339/JAG1-C-Fc protein was developed from mammalian cells and has a target region of C-Fc. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | JAG1 |
| Gene ID | 182 |
| Uniprot ID | JAG1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln34-Ser1046 |
Additional Info
| Function | Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). |
| Protein Name | Protein Jagged-1Jagged1Hj1Cd Antigen Cd339 |
| Database Links | Reactome: R-HSA-2122948Reactome: R-HSA-2644606Reactome: R-HSA-2660826Reactome: R-HSA-2691232Reactome: R-HSA-2894862Reactome: R-HSA-2979096Reactome: R-HSA-8941856Reactome: R-HSA-9013149Reactome: R-HSA-9013423Reactome: R-HSA-9013507Reactome: R-HSA-9013700Reactome: R-HSA-9831926 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Protein Names | Protein Jagged-1 proteinJagged1 proteinHj1 proteinCd Antigen Cd339 proteinJAG1 proteinJAGL1 protein |
Information sourced from Uniprot.org