Human CD32a/FCGR2A (H167) protein (Recombinant-Active) (C-His) (STJP012464)

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STJP012464-100
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Host: Mammalian cells
Applications: ELISA/WB
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human CD32a/FCGR2A (H167)-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Conjugation: Unconjugated
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: FCGR2A
Gene ID: 2212
Uniprot ID: FCG2A_HUMAN
Immunogen Region: Gln34-Ile218 (H167)
Immunogen: Homo sapiens (Human)
Post Translational Modifications Phosphorylated by SRC-type Tyr-kinases such as LYN, BLK, FYN, HCK and SYK.
Function Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A
Igg Fc Receptor Ii-A
Cdw32
Fc-Gamma Rii-A
Fc-Gamma-Riia
Fcrii-A
Cd Antigen Cd32
Database Links Reactome: R-HSA-2029481
Reactome: R-HSA-2029482
Reactome: R-HSA-2029485
Reactome: R-HSA-6798695
Reactome: R-HSA-9664323
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Low Affinity Immunoglobulin Gamma Fc Region Receptor Ii-A protein
Igg Fc Receptor Ii-A protein
Cdw32 protein
Fc-Gamma Rii-A protein
Fc-Gamma-Riia protein
Fcrii-A protein
Cd Antigen Cd32 protein
FCGR2A protein
CD32 protein
FCG2 protein
FCGR2A1 protein
IGFR2 protein

Information sourced from Uniprot.org

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