Human CD312/ADGRE2 protein (Recombinant) (N-His) (STJP006166)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD312/ADGRE2-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ADGRE2 |
| Gene ID | 30817 |
| Uniprot ID | AGRE2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn347-Ser509 |
Additional Info
| Post Translational Modifications | Autoproteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane beta subunit. |
| Function | Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation. |
| Protein Name | Adhesion G Protein-Coupled Receptor E2Egf-Like Module Receptor 2Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 2Cd Antigen Cd312 |
| Database Links | Reactome: R-HSA-373080 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionRuffle MembraneLocalized At The Leading Edge Of Migrating Cells |
| Alternative Protein Names | Adhesion G Protein-Coupled Receptor E2 proteinEgf-Like Module Receptor 2 proteinEgf-Like Module-Containing Mucin-Like Hormone Receptor-Like 2 proteinCd Antigen Cd312 proteinADGRE2 proteinEMR2 protein |
Information sourced from Uniprot.org