Human CD312/ADGRE2 protein (Recombinant) (N-His) (STJP006166)

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STJP006166
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD312/ADGRE2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: ADGRE2
Gene ID: 30817
Uniprot ID: AGRE2_HUMAN
Immunogen Region: Asn347-Ser509
Immunogen: Homo sapiens (Human)
Post Translational Modifications Autoproteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane beta subunit.
Function Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation.
Protein Name Adhesion G Protein-Coupled Receptor E2
Egf-Like Module Receptor 2
Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 2
Cd Antigen Cd312
Database Links Reactome: R-HSA-373080
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cell Projection
Ruffle Membrane
Localized At The Leading Edge Of Migrating Cells
Alternative Protein Names Adhesion G Protein-Coupled Receptor E2 protein
Egf-Like Module Receptor 2 protein
Egf-Like Module-Containing Mucin-Like Hormone Receptor-Like 2 protein
Cd Antigen Cd312 protein
ADGRE2 protein
EMR2 protein

Information sourced from Uniprot.org

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