Human CD307e/FCRL5 protein (Recombinant) (C-His) (STJP007151)

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STJP007151
$633.83 - $3,364.88
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD307e/FCRL5-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: FCRL5
Gene ID: 83416
Uniprot ID: FCRL5_HUMAN
Immunogen Region: Met1-Arg844
Immunogen: Homo sapiens (Human)
Function Plays an important role in B-cell response to antigen that acts both as a negative or positive coreceptor. Inhibits B-cell receptor (BCR) signaling in the absence of CR2 stimulation but engagement with CR2 and the BCR lead to a superior calcium response compared to CR2 and BCR costimulation. May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. May play a role in fertilization.
Protein Name Fc Receptor-Like Protein 5
Fcr-Like Protein 5
Fcrl5
Bxmas1
Fc Receptor Homolog 5
Fcrh5
Immune Receptor Translocation-Associated Protein 2
Cd Antigen Cd307e
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Fc Receptor-Like Protein 5 protein
Fcr-Like Protein 5 protein
Fcrl5 protein
Bxmas1 protein
Fc Receptor Homolog 5 protein
Fcrh5 protein
Immune Receptor Translocation-Associated Protein 2 protein
Cd Antigen Cd307e protein
FCRL5 protein
FCRH5 protein
IRTA2 protein
UNQ503 protein
PRO820 protein

Information sourced from Uniprot.org