Human CD300A protein (Recombinant) (N-His) (STJP016286)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD300A-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | CD300A |
| Gene ID | 11314 |
| Uniprot ID | CLM8_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu18-Pro180 |
Additional Info
| Post Translational Modifications | Phosphorylated on tyrosine. N-glycosylated. |
| Function | Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6. |
| Protein Name | Cmrf35-Like Molecule 8Clm-8Cd300 Antigen-Like Family Member ACmrf-35-H9Cmrf35-H9Cmrf35-HIrc1/Irc2Immunoglobulin Superfamily Member 12Igsf12Inhibitory Receptor Protein 60Irp60Nk Inhibitory ReceptorCd Antigen Cd300a |
| Database Links | Reactome: R-HSA-198933Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cmrf35-Like Molecule 8 proteinClm-8 proteinCd300 Antigen-Like Family Member A proteinCmrf-35-H9 proteinCmrf35-H9 proteinCmrf35-H proteinIrc1/Irc2 proteinImmunoglobulin Superfamily Member 12 proteinIgsf12 proteinInhibitory Receptor Protein 60 proteinIrp60 proteinNk Inhibitory Receptor proteinCd Antigen Cd300a proteinCD300A proteinCMRF35H proteinIGSF12 proteinHSPC083 protein |
Information sourced from Uniprot.org