Human CD273/PD-L2/PDCD1LG2 protein (Recombinant) (C-His) (STJP005928)

SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
STJP005928
🚚 Free UK Delivery on orders over £150
Processing The item has been added
Enquire For Bulk Order
✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

General Information

Short DescriptionRecombinant-Human CD273/PD-L2/PDCD1LG2-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolPDCD1LG2
Gene ID80380
Uniprot IDPD1L2_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionMet1-Thr220

Additional Info

Function Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Protein Name Programmed Cell Death 1 Ligand 2
Pd-1 Ligand 2
Pd-L2
Pdcd1 Ligand 2
Programmed Death Ligand 2
Butyrophilin B7-Dc
B7-Dc
Cd Antigen Cd273
Database Links Reactome: R-HSA-389948
Cellular Localisation Isoform 3: Secreted
Isoform 2: Endomembrane System
Single-Pass Type I Membrane Protein
Isoform 1: Cell Membrane
Alternative Protein Names Programmed Cell Death 1 Ligand 2 protein
Pd-1 Ligand 2 protein
Pd-L2 protein
Pdcd1 Ligand 2 protein
Programmed Death Ligand 2 protein
Butyrophilin B7-Dc protein
B7-Dc protein
Cd Antigen Cd273 protein
PDCD1LG2 protein
B7DC protein
CD273 protein
PDCD1L2 protein
PDL2 protein

Information sourced from Uniprot.org

Citations

Product Review