Human CD273/PD-L2/PDCD1LG2 protein (Recombinant) (C-His) (STJP005928)
SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD273/PD-L2/PDCD1LG2-C-His protein was developed from mammalian cells for the region C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | PDCD1LG2 |
| Gene ID | 80380 |
| Uniprot ID | PD1L2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Thr220 |
Additional Info
| Function | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| Protein Name | Programmed Cell Death 1 Ligand 2Pd-1 Ligand 2Pd-L2Pdcd1 Ligand 2Programmed Death Ligand 2Butyrophilin B7-DcB7-DcCd Antigen Cd273 |
| Database Links | Reactome: R-HSA-389948 |
| Cellular Localisation | Isoform 3: SecretedIsoform 2: Endomembrane SystemSingle-Pass Type I Membrane ProteinIsoform 1: Cell Membrane |
| Alternative Protein Names | Programmed Cell Death 1 Ligand 2 proteinPd-1 Ligand 2 proteinPd-L2 proteinPdcd1 Ligand 2 proteinProgrammed Death Ligand 2 proteinButyrophilin B7-Dc proteinB7-Dc proteinCd Antigen Cd273 proteinPDCD1LG2 proteinB7DC proteinCD273 proteinPDCD1L2 proteinPDL2 protein |
Information sourced from Uniprot.org