SDS-PAGE gel showing recombinant human CD27 ligand CD70 protein under reducing conditions

Human CD27 Ligand/CD70 protein (Recombinant) (His-Tag) (STJP019085)

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STJP019085
£134.50 - £738.50
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Short Description :Recombinant-Human CD27 Ligand/CD70-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE/Denatured
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:CD70
Gene ID:970
Uniprot ID:CD70_HUMAN
Accession Number:NP_001243
Immunogen:Human
Immunogen Region:39-193aa
Immunogen Sequence:QRFAQAQ QQLPLESLGW DVAELQLNHT GPQQDPRLYW QGGPALGRSF LHGPELDKGQ LRIHRDGIYM VHIQVTLAIC SSTTASRHHP TTLAVGICSP ASRSISLLRL SFHQGCTIAS QRLTPLARGD TLCTNLTGTL LPSRNTDETF FGVQWVRP
Post Translational Modifications N-glycosylated.
Function Expressed at the plasma membrane of B cells, it is the ligand of the CD27 receptor which is specifically expressed at the surface of T cells. The CD70-CD27 signaling pathway mediates antigen-specific T cell activation and expansion which in turn provides immune surveillance of B cells.
Protein Name Cd70 Antigen
Cd27 Ligand
Cd27-L
Tumor Necrosis Factor Ligand Superfamily Member 7
Cd Antigen Cd70
Database Links Reactome: R-HSA-5669034
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Cd70 Antigen protein
Cd27 Ligand protein
Cd27-L protein
Tumor Necrosis Factor Ligand Superfamily Member 7 protein
Cd Antigen Cd70 protein
CD70 protein
CD27L protein
CD27LG protein
TNFSF7 protein

Information sourced from Uniprot.org

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