Human CD265/TNFRSF11A protein (Recombinant-Active) (C-His) (STJP012775)

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STJP012775-100
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Short Description :Recombinant-Active-Human CD265/TNFRSF11A-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications:ELISA/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Conjugation:Unconjugated
Dilution Range:Reconstitute in sterile water for a stock solution.
Formulation:Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin:< 1 EU/µg as determined by LAL test.
Gene Symbol:TNFRSF11A
Gene ID:8792
Uniprot ID:TNR11_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Ile30-Pro212
Function Receptor for TNFSF11/RANKL/TRANCE/OPGL.essential for RANKL-mediated osteoclastogenesis. Its interaction with EEIG1 promotes osteoclastogenesis via facilitating the transcription of NFATC1 and activation of PLCG2. Involved in the regulation of interactions between T-cells and dendritic cells.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 11a
Osteoclast Differentiation Factor Receptor
Odfr
Receptor Activator Of Nf-Kb
Cd Antigen Cd265
Database Links Reactome: R-HSA-5668541
Reactome: R-HSA-5676594
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Membrane Raft
Isoform Rank-E5a: Cell Membrane
Alternative Protein Names Tumor Necrosis Factor Receptor Superfamily Member 11a protein
Osteoclast Differentiation Factor Receptor protein
Odfr protein
Receptor Activator Of Nf-Kb protein
Cd Antigen Cd265 protein
TNFRSF11A protein
RANK protein

Information sourced from Uniprot.org

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