Human CD253/TNFSF10/TRAIL protein (Recombinant) (Tag free) (STJP012606)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD253/TNFSF10/TRAIL-Tag free protein was developed from e.coli and has a target region of Tag free. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in 40mM Tris-HCl, 300mM NaCl, 5% Trehalose, 5% Mannitol, 0.01% Tween80, 10% Glycerol, pH 7.0. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for this information. |
Target Information
| Gene Symbol | TNFSF10 |
| Gene ID | 8743 |
| Uniprot ID | TNF10_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Arg115-Gly281 |
Additional Info
| Post Translational Modifications | Tyrosine phosphorylated by PKDCC/VLK. |
| Function | Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 10Apo-2 LigandApo-2lTnf-Related Apoptosis-Inducing LigandProtein TrailCd Antigen Cd253 |
| Database Links | Reactome: R-HSA-140534Reactome: R-HSA-3371378Reactome: R-HSA-5213460Reactome: R-HSA-5218900Reactome: R-HSA-69416Reactome: R-HSA-75158 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinSecretedExists Both As Membrane-Bound And Soluble Form |
| Alternative Protein Names | Tumor Necrosis Factor Ligand Superfamily Member 10 proteinApo-2 Ligand proteinApo-2l proteinTnf-Related Apoptosis-Inducing Ligand proteinProtein Trail proteinCd Antigen Cd253 proteinTNFSF10 proteinAPO2L proteinTRAIL protein |
Information sourced from Uniprot.org