Human CD253/TNFSF10/TRAIL protein (Recombinant) (N-His) (STJP004854)

Name: Human CD253/TNFSF10/TRAIL protein (Recombinant) (N-His) (STJP004854)
SKU: STJP004854
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHomo sapiens (Human)

STJP004854

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Short Description	Recombinant-Human CD253/TNFSF10/TRAIL-N-His protein was developed from e.coli for the region N-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	Tyrosine phosphorylated by PKDCC/VLK.
Function	Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.
Protein Name	Tumor Necrosis Factor Ligand Superfamily Member 10 Apo-2 Ligand Apo-2l Tnf-Related Apoptosis-Inducing Ligand Protein Trail Cd Antigen Cd253
Database Links	Reactome: R-HSA-140534 Reactome: R-HSA-3371378 Reactome: R-HSA-5213460 Reactome: R-HSA-5218900 Reactome: R-HSA-69416 Reactome: R-HSA-75158
Cellular Localisation	Cell Membrane Single-Pass Type Ii Membrane Protein Secreted Exists Both As Membrane-Bound And Soluble Form
Alternative Protein Names	Tumor Necrosis Factor Ligand Superfamily Member 10 protein Apo-2 Ligand protein Apo-2l protein Tnf-Related Apoptosis-Inducing Ligand protein Protein Trail protein Cd Antigen Cd253 protein TNFSF10 protein APO2L protein TRAIL protein

Information sourced from Uniprot.org