Human CD218b/IL18RAP protein (Recombinant-Active) (C-His) (STJP012337)

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STJP012337-100
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Host: Mammalian Cells
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Active-Human CD218b/IL18RAP-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Dilution Range: Reconstitute in sterile water for a stock solution.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin: <0.1 EU/Mu g of the protein by the LAL method.
Gene Symbol: IL18RAP
Gene ID: 8807
Uniprot ID: I18RA_HUMAN
Immunogen Region: Phe20-Arg356
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-glycosylated.
Function Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).
Protein Name Interleukin-18 Receptor Accessory Protein
Il-18 Receptor Accessory Protein
Il-18racp
Accessory Protein-Like
Acpl
Cd218 Antigen-Like Family Member B
Cdw218b
Il-1r Accessory Protein-Like
Il-1racpl
Interleukin-1 Receptor 7
Il-1r-7
Il-1r7
Interleukin-18 Receptor Accessory Protein-Like
Interleukin-18 Receptor Beta
Il-18r-Beta
Il-18rbeta
Cd Antigen Cd218b
Database Links Reactome: R-HSA-9012546
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Interleukin-18 Receptor Accessory Protein protein
Il-18 Receptor Accessory Protein protein
Il-18racp protein
Accessory Protein-Like protein
Acpl protein
Cd218 Antigen-Like Family Member B protein
Cdw218b protein
Il-1r Accessory Protein-Like protein
Il-1racpl protein
Interleukin-1 Receptor 7 protein
Il-1r-7 protein
Il-1r7 protein
Interleukin-18 Receptor Accessory Protein-Like protein
Interleukin-18 Receptor Beta protein
Il-18r-Beta protein
Il-18rbeta protein
Cd Antigen Cd218b protein
IL18RAP protein
IL1R7 protein

Information sourced from Uniprot.org

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