| Short Description : | Recombinant-Active-Human CD204/MSR1-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications. |
| Applications: | ELISA/WB |
| Host: | Mammalian Cells |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Conjugation: | Unconjugated |
| Dilution Range: | Reconstitute in sterile water for a stock solution. |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin: | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity: | Measured by its binding ability in a functional ELISA. Immobilised recombinant human CD204/MSR1 at 5 µg/mL (100 µL/well) can bind biotinylated advanced glycation endproducts of bovine serum albumin (AGEBSA) with a linear range of 6-400 ng/mL. |
| Gene Symbol: | MSR1 |
| Gene ID: | 4481 |
| Uniprot ID: | MSRE_HUMAN |
| Immunogen: | Homo sapiens (Human) |
| Immunogen Region: | Lys77-Leu451 |
| Function | Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL. |
| Protein Name | Macrophage Scavenger Receptor Types I And IiMacrophage Acetylated Ldl Receptor I And IiScavenger Receptor Class A Member 1Cd Antigen Cd204 |
| Database Links | Reactome: R-HSA-3000480 |
| Cellular Localisation | MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | Macrophage Scavenger Receptor Types I And Ii proteinMacrophage Acetylated Ldl Receptor I And Ii proteinScavenger Receptor Class A Member 1 proteinCd Antigen Cd204 proteinMSR1 proteinSCARA1 protein |
Information sourced from Uniprot.org
