Human CD20 protein (Recombinant) (STJP000412)

Name: Human CD20 protein (Recombinant) (STJP000412)
SKU: STJP000412
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostHEK293

ConjugationUnconjugated

ImmunogenOptimized DNA sequence encoding cytoplasmic domain of human CD20 including a N-terminal 6His tag was expressed in HEK293 cells. NA

STJP000412

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Short Description	Recombinant-Human CD20-protein was developed from hek293. For use in research applications.
Host	HEK293
Note	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Formulation	0.2 Mu m filtered PBS solution, pH7.2.
Storage Instruction	Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA

Gene Symbol	MS4A1
Gene ID	931
Uniprot ID	CD20_HUMAN
Immunogen	Optimized DNA sequence encoding cytoplasmic domain of human CD20 including a N-terminal 6His tag was expressed in HEK293 cells. NA
Immunogen Region	Cytoplasmic domain

Tissue Specificity	Expressed on B-cells.
Post Translational Modifications	Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate.
Function	B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
Protein Name	B-Lymphocyte Antigen Cd20 B-Lymphocyte Surface Antigen B1 Bp35 Leukocyte Surface Antigen Leu-16 Membrane-Spanning 4-Domains Subfamily A Member 1 Cd Antigen Cd20
Database Links
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein Lipid-Anchor Constitutively Associated With Membrane Rafts
Alternative Protein Names	B-Lymphocyte Antigen Cd20 protein B-Lymphocyte Surface Antigen B1 protein Bp35 protein Leukocyte Surface Antigen Leu-16 protein Membrane-Spanning 4-Domains Subfamily A Member 1 protein Cd Antigen Cd20 protein MS4A1 protein CD20 protein

Information sourced from Uniprot.org