Human CD20 protein (Recombinant) (STJP000412)

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STJP000412
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD20-protein was developed from hek293. For use in research applications.
Conjugation: Unconjugated
Formulation: 0.2 Mu m filtered PBS solution, pH7.2.
Storage Instruction: Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA
Gene Symbol: MS4A1
Gene ID: 931
Uniprot ID: CD20_HUMAN
Immunogen Region: Cytoplasmic domain
Immunogen: Optimized DNA sequence encoding cytoplasmic domain of human CD20 including a N-terminal 6His tag was expressed in HEK293 cells. NA
Tissue Specificity Expressed on B-cells.
Post Translational Modifications Phosphorylated on serines and threonines in resting B-cells. Protein kinase C/PKC can use CD20 as substrate.
Function B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
Protein Name B-Lymphocyte Antigen Cd20
B-Lymphocyte Surface Antigen B1
Bp35
Leukocyte Surface Antigen Leu-16
Membrane-Spanning 4-Domains Subfamily A Member 1
Cd Antigen Cd20
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Lipid-Anchor
Constitutively Associated With Membrane Rafts
Alternative Protein Names B-Lymphocyte Antigen Cd20 protein
B-Lymphocyte Surface Antigen B1 protein
Bp35 protein
Leukocyte Surface Antigen Leu-16 protein
Membrane-Spanning 4-Domains Subfamily A Member 1 protein
Cd Antigen Cd20 protein
MS4A1 protein
CD20 protein

Information sourced from Uniprot.org

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