Name: Human CD191/CCR1 protein (Recombinant) (N-GST) (STJP004560)
SKU: STJP004560
Availability: InStock

Human CD191/CCR1 protein (Recombinant) (N-GST) (STJP004560)

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STJP004560

£328.50 - £1,437.50

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Host:	E. coli
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description :	Recombinant-Human CD191/CCR1-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.

Formulation:	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Function	Chemokine receptor that plays a crucial role in regulating immune cell migration, inflammation, and immune responses. Contributes to the inflammatory response by recruiting immune cells, such as monocytes, macrophages, T-cells, and dendritic cells, to sites of inflammation for the clearance of pathogens and the resolution of tissue damage. When activated by its ligands including CCL3, CCL5-9, CCL13-16 and CCL23, triggers a signaling cascade within immune cells, leading to their migration towards the source of the chemokine. For example, mediates neutrophil migration after activation by CCL3 leading to the sequential release of TNF-alpha and leukotriene B4. Mediates also monocyte migration upon CXCL4 binding. Activation by CCL5 results in neuroinflammation through the ERK1/2 signaling pathway.
Protein Name	C-C Chemokine Receptor Type 1 C-C Ckr-1 Cc-Ckr-1 Ccr-1 Ccr1 Hm145 Ld78 Receptor Macrophage Inflammatory Protein 1-Alpha Receptor Mip-1alpha-R Rantes-R Cd Antigen Cd191
Database Links	Reactome: R-HSA-380108 Reactome: R-HSA-418594 Reactome: R-HSA-6783783
Cellular Localisation	Cell Membrane Multi-Pass Membrane Protein
Alternative Protein Names	C-C Chemokine Receptor Type 1 protein C-C Ckr-1 protein Cc-Ckr-1 protein Ccr-1 protein Ccr1 protein Hm145 protein Ld78 Receptor protein Macrophage Inflammatory Protein 1-Alpha Receptor protein Mip-1alpha-R protein Rantes-R protein Cd Antigen Cd191 protein CCR1 protein CMKBR1 protein CMKR1 protein SCYAR1 protein

Information sourced from Uniprot.org

Model	Name	Host
STJP006816	Human CD191/CCR1 protein (Recombinant) (N-His) (STJP006816)	E. coli
STJP003515	Human MYC protein (Recombinant) (N-GST) (STJP003515)	E. coli
STJP003636	Human SLPI protein (Recombinant) (N-GST) (STJP003636)	E. coli
STJP007291	Human MXI1 protein (Recombinant) (N-GST) (STJP007291)	E. coli
STJP003265	Human AQP9 protein (Recombinant) (N-GST) (STJP003265)	E. coli

Human CD191/CCR1 protein (Recombinant) (N-GST) (STJP004560)

General Information