Human CD182/CXCR2 protein (Recombinant) (N-GST) (STJP004408)

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STJP004408
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD182/CXCR2-N-GST protein was developed from e. coli and has a target region of N-GST. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CXCR2
Gene ID: 3579
Uniprot ID: CXCR2_HUMAN
Immunogen Region: Met1-Leu57
Immunogen: Homo sapiens (Human)
Function Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Protein Name C-X-C Chemokine Receptor Type 2
Cxc-R2
Cxcr-2
Cdw128b
Gro/Mgsa Receptor
High Affinity Interleukin-8 Receptor B
Il-8r B
Il-8 Receptor Type 2
Cd Antigen Cd182
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Protein Names C-X-C Chemokine Receptor Type 2 protein
Cxc-R2 protein
Cxcr-2 protein
Cdw128b protein
Gro/Mgsa Receptor protein
High Affinity Interleukin-8 Receptor B protein
Il-8r B protein
Il-8 Receptor Type 2 protein
Cd Antigen Cd182 protein
CXCR2 protein
IL8RB protein

Information sourced from Uniprot.org

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