Human CD16b/FCGR3B protein (Recombinant) (C-His) (STJP006997)

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STJP006997
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Short Description :Recombinant-Human CD16b/FCGR3B-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
Applications:ELISA/Immunogen/SDS-PAGE/WB
Host:Mammalian Cells
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Dilution Range:Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Formulation:Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction:Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol:FCGR3B
Gene ID:2215
Uniprot ID:FCG3B_HUMAN
Immunogen:Homo sapiens (Human)
Immunogen Region:Met1-Ser200
Post Translational Modifications Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3. The soluble form is produced by a proteolytic cleavage.
Function Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Protein Name Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B
Fc-Gamma Riii-Beta
Cd16-I
Fc-Gamma Riii
Fc-Gamma Riiib
Fcriii
Fcriiib
Fcr-10
Igg Fc Receptor Iii-1
Cd Antigen Cd16b
Database Links Reactome: R-HSA-163125
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Secreted
Secreted After Cleavage
Alternative Protein Names Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B protein
Fc-Gamma Riii-Beta protein
Cd16-I protein
Fc-Gamma Riii protein
Fc-Gamma Riiib protein
Fcriii protein
Fcriiib protein
Fcr-10 protein
Igg Fc Receptor Iii-1 protein
Cd Antigen Cd16b protein
FCGR3B protein
CD16B protein
FCG3 protein
FCGR3 protein
IGFR3 protein

Information sourced from Uniprot.org

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