Human CD158b2/KIR2DL3 protein (Recombinant) (No-Tag) (STJP019693)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CD158b2/KIR2DL3-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 7.5) |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KIR2DL3 |
| Gene ID | 3804 |
| Uniprot ID | KI2L3_HUMAN |
| Accession Number | NP_056952.2 |
| Immunogen | Human |
| Immunogen Region | 23-223aa |
| Immunogen Sequence | MEGVHRKPSL LAHPGPLVKS EETVILQCWS DVRFQHFLLH REGKFKDTLH LIGEHHDGIS KANFSIGPMM QDLAGTYRCY GSVTHSPYQL SAPSDPLDIV ITGLYEKPSL SAQPGPTVLA GESVTLSCSS RSSYDMYHLS REGEAHERRF SAGPKVNGTF QADFPLGPAT HGGTYRCFGS FRDSPYEWSN SSDPLLVSVT GN |
Additional Info
| Function | Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 2dl3Cd158 Antigen-Like Family Member B2Kir-023gbKiller Inhibitory Receptor Cl 2-3Nkat2aNkat2bNatural Killer-Associated Transcript 2Nkat-2P58 Natural Killer Cell Receptor Clone Cl-6P58 Nk Receptor Cl-6P58.2 Mhc Class-I-Specific Nk ReceptorCd Antigen Cd158b2 |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Killer Cell Immunoglobulin-Like Receptor 2dl3 proteinCd158 Antigen-Like Family Member B2 proteinKir-023gb proteinKiller Inhibitory Receptor Cl 2-3 proteinNkat2a proteinNkat2b proteinNatural Killer-Associated Transcript 2 proteinNkat-2 proteinP58 Natural Killer Cell Receptor Clone Cl-6 proteinP58 Nk Receptor Cl-6 proteinP58.2 Mhc Class-I-Specific Nk Receptor proteinCd Antigen Cd158b2 proteinKIR2DL3 proteinCD158B2 proteinKIRCL23 proteinNKAT2 protein |
Information sourced from Uniprot.org