Human CD100/SEMA4D protein (Recombinant) (N-His) (STJP005796)

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STJP005796
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD100/SEMA4D-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: SEMA4D
Gene ID: 10507
Uniprot ID: SEM4D_HUMAN
Immunogen Region: Phe502-Phe636
Immunogen: Homo sapiens (Human)
Function Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells. Plays a role in the immune system.induces B-cells to aggregate and improves their viability (in vitro). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway.
Protein Name Semaphorin-4d
A8
Bb18
Gr3
Cd Antigen Cd100
Database Links Reactome: R-HSA-416550
Reactome: R-HSA-416572
Reactome: R-HSA-416700
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Protein Names Semaphorin-4d protein
A8 protein
Bb18 protein
Gr3 protein
Cd Antigen Cd100 protein
SEMA4D protein
C9orf164 protein
CD100 protein
SEMAJ protein

Information sourced from Uniprot.org

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