| Host: |
E.coli |
| Applications: |
SDS-PAGE |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : |
Recombinant-Human CD-M6PR-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Formulation: |
Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Concentration: |
0.5 mg/mL |
| Storage Instruction: |
For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
M6PR |
| Gene ID: |
4074 |
| Uniprot ID: |
MPRD_HUMAN |
| Immunogen Region: |
27-185aa |
| Accession Number: |
NP_002346 |
| Immunogen: |
Human |
| Immunogen Sequence: |
TEEKTCD LVGEKGKESE KELALVKRLK PLFNKSFEST VGQGSDTYIY IFRVCREAGN HTSGAGLVQI NKSNGKETVV GRLNETHIFN GSNWIMLIYK GGDEYDNHCG KEQRRAVVMI SCNRHTLADN FNPVSEERGK VQDCFYLFEM DSSLACSPEI SH |
| Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. |
| Protein Name | Cation-Dependent Mannose-6-Phosphate ReceptorCd Man-6-P ReceptorCd-Mpr46 Kda Mannose 6-Phosphate ReceptorMpr 46 |
| Database Links | Reactome: R-HSA-432720Reactome: R-HSA-6811440Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-9840310 |
| Cellular Localisation | Lysosome MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cation-Dependent Mannose-6-Phosphate Receptor proteinCd Man-6-P Receptor proteinCd-Mpr protein46 Kda Mannose 6-Phosphate Receptor proteinMpr 46 proteinM6PR proteinMPR46 proteinMPRD protein |
Information sourced from Uniprot.org
