Human CCL8/MCP-2 protein (Recombinant) (N-His) (STJP005084)

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STJP005084
£328.50 - £1,437.50
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCL8/MCP-2-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CCL8
Gene ID: 6355
Uniprot ID: CCL8_HUMAN
Immunogen Region: Ser29-Pro99
Immunogen: Homo sapiens (Human)
Post Translational Modifications N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.
Function Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8.
Protein Name C-C Motif Chemokine 8
Hc14
Monocyte Chemoattractant Protein 2
Monocyte Chemotactic Protein 2
Mcp-2
Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 8 protein
Hc14 protein
Monocyte Chemoattractant Protein 2 protein
Monocyte Chemotactic Protein 2 protein
Mcp-2 protein
Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 protein
CCL8 protein
MCP2 protein
SCYA10 protein
SCYA8 protein

Information sourced from Uniprot.org