Human CCL3/MIP-1 alpha protein (Recombinant) (His-Tag) (STJP017155)

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STJP017155
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Host: E.coli
Applications: SDS-PAGE
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCL3/MIP-1 alpha-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Formulation: Liquid in 10mM Sodium Citrate buffer (pH 3.5) containing 20% Glycerol
Concentration: 0.25 mg/mL
Storage Instruction: For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin: < 1 EU per 1ug of protein (determined by LAL method)
Gene Symbol: CCL3
Gene ID: 6348
Uniprot ID: CCL3_HUMAN
Immunogen Region: 24-92aa
Accession Number: NP_002974.1
Immunogen: Human
Immunogen Sequence: SLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
Post Translational Modifications N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.
Function Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Protein Name C-C Motif Chemokine 3
G0/G1 Switch Regulatory Protein 19-1
Macrophage Inflammatory Protein 1-Alpha
Mip-1-Alpha
Pat 464.1
Sis-Beta
Small-Inducible Cytokine A3
Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69
Ld78-Alpha(4-69
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-6783783
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 3 protein
G0/G1 Switch Regulatory Protein 19-1 protein
Macrophage Inflammatory Protein 1-Alpha protein
Mip-1-Alpha protein
Pat 464.1 protein
Sis-Beta protein
Small-Inducible Cytokine A3 protein
Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69 protein
Ld78-Alpha(4-69 protein
CCL3 protein
G0S19-1 protein
MIP1A protein
SCYA3 protein

Information sourced from Uniprot.org

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