Human CCL25/TECK protein (Recombinant) (N-His) (STJP003245)

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STJP003245
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CCL25/TECK-N-His protein was developed from e. coli and has a target region of N-His. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: CCL25
Gene ID: 6370
Uniprot ID: CCL25_HUMAN
Immunogen Region: Gln24-Leu150
Immunogen: Homo sapiens (Human)
Function Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Protein Name C-C Motif Chemokine 25
Chemokine Teck
Small-Inducible Cytokine A25
Thymus-Expressed Chemokine
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 25 protein
Chemokine Teck protein
Small-Inducible Cytokine A25 protein
Thymus-Expressed Chemokine protein
CCL25 protein
SCYA25 protein
TECK protein

Information sourced from Uniprot.org